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Deferiprone in Friedreich ataxia: a 6-month randomized controlled trial

Microvascular occlusions are not related to the number of irreversibly sickled cells, but instead may be dependent on more subtle red cell membrane damage and local factors, such as inflammation or vasoconstriction, that tend to slow or arrest the movement of red cells through microvascular beds (see Fig

A.SavonenK.HassinenM.KiviniemiV.et al (2010)

10.1038/nrm3801 37 HolmstrmK

It contains discussions of the principles fleshed out here in greater detail, supplement recommendations, and a searchable database of glutathione in 285 foods

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